推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 61 kDa
物種活性
human, rat, mouse
濃度
~1 mg/mL
技術
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... HSPD1(3329)
一般說明
Anti-HSP60 antibody detects endogenous levels of total HSP60 protein.
Hsp60 (heat shock protein family D member 1) is a mitochondrial chaperone, located in the endoplasmic reticulum (ER). It is mapped to human chromosome 2q33.1.
免疫原
The antiserum was produced against synthesized peptide derived from human HSP60.
Immunogen Range: 511-560
Immunogen Range: 511-560
應用
Anti-HSP60, C-Terminal antibody has been used in SDS/PAGE and western blot analysis.
生化/生理作用
Hsp60 (heat shock protein family D member 1) helps to gather proteins that are imported into mitochondrial matrix. Overexpression of Hsp60 results in Behcet′s Disease (BD),Crohn′s disease, juvenile dermatomyositis (JDM), and juvenile idiopathic arthritis (JIA) and rheumatoid arthritis (RA).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation
Febs Letters, 590(19), 3309-3322 (2016)
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
Nature, 337(6208), 620-625 (1989)
HSPD1 (heat shock 60kDa protein 1)
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2007)
HSP60: a double edge sword in autoimmunity
Oncotarget, 6(32), 32299-32300 (2015)
Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis
Scientific Reports (2015)
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