SAB4300041

Anti-phospho-ATF4 (pSer²⁴⁵) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-CREB-2 antibody produced in rabbit, Anti-CREB2 antibody produced in rabbit, Anti-TAXREB67 antibody produced in rabbit, Anti-TXREB antibody produced in rabbit, Anti-activating transcription factor 4 (tax-responsive enhancer element B67) antibody produced in rabbit
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~45 kDa
• 物種活性: human
• 濃度: 1 mg/mL
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• 同型: IgG
• 免疫原序列: (N-R-SP-L-P)
• NCBI登錄號: NP_001666.2
• UniProt登錄號: P18848
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer245)
• 基因資訊: human ... ATF4(468)

说明

免疫原

Peptide sequence around phosphorylation site of serine 245 (N-R-S(p)-L-P), according to the protein ATF4.

特點和優勢

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標靶描述

ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable