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Key Documents

SAB3500380

Sigma-Aldrich

Anti-LXR-B antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-LXRB, Anti-Liver X receptor B, Anti-NR1H2, Anti-Nuclear receptor subfamily 1 group H member 2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, human, rat

技術

indirect ELISA: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NR1H2(7376)

一般說明

Liver X receptor β (LXRβ ) is a member of LXRs that belong to the nuclear receptor superfamily. It possesses a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The protein is expressed in many tissues and the LXRβ gene is localized on human chromosome 19q13.3.

免疫原

LXR-B antibody was raised against a 14 amino acid peptide from near the amino terminus human LXR-B.

生化/生理作用

Liver X receptor β (LXRβ) has a role in cell death and cholesterol metabolism. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

聯結

The action of this antibody can be blocked using blocking peptide SBP3500380.

外觀

Supplied in PBS with 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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说明
价格

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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访问文档库

A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.
Mouzat K
BMC Medical Genetics (2011)
Liver X receptor ? activation induces pyroptosis of human and murine colon cancer cells.
Derangere V
Cell Death and Differentiation (2014)
Liver x receptors in atherosclerosis and inflammation.
Im SS and Osborne TF
Circulation Research (2011)

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