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Merck
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主要文件

SAB1103857

Sigma-Aldrich

Anti-MUSTN1 (6-20) antibody produced in rabbit

IgG fraction of antiserum

别名:

Anti-Musculoskeletal, embryonic nuclear protein 1, Anti-Mustang

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~9 kDa

物種活性

human

技術

western blot: 1:500-1:2,000

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MUSTN1(389125)

一般說明

MUSTN1 gene was initially discovered in fracture callus tissue. The gene codes for a small nuclear protein and is known to be widely expressed in skeletal muscle. MUSTN1 expression is observed during embryogenesis in the developing muscles and somites. Its maximum expression is observed from the third month of life. The gene is highly conserved among the vertebrates. The gene is known to contain a nuclear localization sequence, phosphorylation and myristoylation sites.
Musculoskeletal, embryonic nuclear protein 1 (MUSTN1) is encoded by the gene is mapped to human chromosome 3p21.1.

免疫原

synthetic peptide corresponding to amino acids 6-20of human MUSTN1

生化/生理作用

MUSTN1 is involved in bone development and regeneration, as well as chondrogenesis. It is critical in the regulation of myogenic differentiation and myofusion as its knock-down inhibits the processes.

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Robert P Gersch et al.
Bone, 45(2), 330-338 (2009-05-05)
Mustn1 encodes a small nuclear protein expressed specifically in the musculoskeletal system that was originally identified as a strongly up-regulated gene during bone regeneration, especially in fracture callus proliferating chondrocytes. Further experiments were undertaken to investigate its expression and role
Cheng Liu et al.
American journal of physiology. Cell physiology, 298(5), C1100-C1108 (2010-02-05)
Mustn1 (Mustang, musculoskeletal temporally activated novel gene) was originally identified in fracture callus tissue, but its greatest expression is detected in skeletal muscle. Thus, we conducted experiments to investigate the expression and function of Mustn1 during myogenesis. Temporally, quantitative real-time
Allelic expression analysis of the osteoarthritis susceptibility locus that maps to chromosome 3p21 reveals cis-acting eQTLs at GNL3 and SPCS1
Gee F, et al.
BMC Medical Genetics, 15(1), 53-53 (2014)

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