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Merck
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Key Documents

ABD115

Sigma-Aldrich

Anti-MUSTN1

from rabbit, purified by affinity chromatography

别名:

Musculoskeletal embryonic nuclear protein 1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human, mouse

物種活性(以同源性預測)

rat (based on 100% sequence homology)

包裝

antibody small pack of 25 μg

技術

immunohistochemistry: suitable (paraffin)
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

ambient

目標翻譯後修改

unmodified

基因資訊

human ... MUSTN1(389125)

一般說明

Musculoskeletal embryonic nuclear protein 1 (UniProt: Q8IVN3; also known a MUSTN1) is encoded by the MUSTN1 gene (Gene ID: 389125) in human. MUSTN1 is a small protein of the MUSTANG family that is found predominantly in the musculoskeletal system. It plays a role in the development and regeneration of the musculoskeletal system. It localizes to the nucleus and specifically, spatially in mesenchymal cells of the developing limbs and in the fracture callus in periosteal osteoprogenitor cells, proliferating chondrocytes, and young active osteoblasts. MUSTN1 sequence is highly homologous in vertebrates and contains a nuclear localization sequence without any other significant motifs. MUSTN1 is highly expressed during embryogenesis and is essential for chondrocyte proliferation and differentiation. (Ref.: Gersch, RP and Hadjiargyrou, M (2009). Bone 45(2); 330-338).

特異性

This rabbit polyclonal antibody detects Musculoskeletal embryonic nuclear protein 1 (MUSTN1) in human and mouse. It targets an epitope within 12 amino acids from the C-terminal region.

免疫原

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to 12 amino acids from the C-terminal region of human Musculoskeletal embryonic nuclear protein 1.

應用

Anti-MUSTN1, Cat. No. ABD115, is a rabbit polyclonal antibody that detects human and murine Musculoskeletal embryonic nuclear protein 1 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting.
Research Category
Cell Structure
Western Blotting Analysis: 2 µg/mL from a representative lot detected MUSTN1 in human heart tissue lysate.
Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected MUSTN1 in human skeletal muscle, mouse embryo, and mouse embryonic lung tissues.
Western Blotting Analysis: 2 µg/mL from a representative lot detected MUSTN1 in human heart tissue lysate.

Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected MUSTN1 in human skeletal muscle, mouse embryo, and mouse embryonic lung tissues.

品質

Evaluated by Western Blotting in C2C12 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected MUSTN1 in C2C12 cell lysate.

標靶描述

~13 kDa observed; 8.91 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

外觀

Affinity Purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 0.15 M NaCl, pH7.4 with 0.05% sodium azide.
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 0.15 M NaCl, pH7.4 with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.
Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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水污染物質分類(WGK)

WGK 1


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