S3322

超肉桂醛

≥98% (HPLC)

• 别名: 1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
• 经验公式（希尔记法）: C₁₂H₁₁NO₂
• CAS号: 70351-51-8
• 分子量: 201.22
• MDL號碼: MFCD08530327
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329824530
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: faintly red to very dark red
• 溶解度: DMSO: 10 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CN1C(=O)C(=C\C(C)=O)\c2ccccc12
• InChI: 1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+
• InChI 密鑰: CZKBLHCEDVWPRN-JXMROGBWSA-N

说明

應用

Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.

生化／生理作用

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator. EC₅₀ = 0.8 μM.

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC₅₀ = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

注意

Air-sensitive

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves