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product name
精胺 四盐酸盐, powder or crystals
形狀
powder or crystals
品質等級
mp
310-311 °C (dec.) (lit.)
溶解度
water, high purity: 100 mg/ml
儲存溫度
room temp
SMILES 字串
Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
InChI
1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChI 密鑰
XLDKUDAXZWHPFH-UHFFFAOYSA-N
基因資訊
human ... GRIN1(2902)
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應用
四盐酸精胺用于沉淀新鲜冷冻乳腺癌组织、 涎腺存档组织、肾和甲状腺肿瘤 以及鸡红细胞的 DNA，以进行流式细胞分析。
用于从低盐缓冲液中沉淀 DNA。
生化／生理作用
多胺位点混合型 NMDA 激动-拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 激动-拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
精胺是一种多胺，来源于亚精胺，是真核生物细胞生长所必需的。它充当基因表达的调节剂，抑制DNA损伤并通过充当自由基清除剂来保护细胞免受损害。 在蛋白质组学研究中，精胺介导 DNA 结合蛋白快速结晶。
準備報告
四盐酸精胺在100mg / ml的水中生成澄清、无色至淡黄色水溶液。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
E Bergers et al.
Journal of clinical pathology, 49(11), 931-937 (1996-11-01)
Conflicting results have been reported concerning the prognostic value of DNA flow cytometric variables (DNA ploidy, DNA index, %S phase fraction) in breast cancer. Selection bias and differences in treatment may have contributed to these conflicting prognostic results. Differences in
A S Jackson et al.
The British journal of nutrition, 40(3), 497-504 (1978-11-01)
1. Skinfold thickness, body circumferences and body density were measured in samples of 308 and ninety-five adult men ranging in age from 18 to 61 years. 2. Using the sample of 308 men, multiple regression equations were calculated to estimate
J Griffith et al.
Biochemistry, 24(1), 158-162 (1985-01-01)
The RecA protein of Escherichia coli, whether pure or in a crude cell lysate, will rapidly form small crystals (microcrystals) in the presence of low concentrations of spermidine. We describe the conditions of time, pH, and polyamine concentration over which
L L Vindeløv et al.
Cytometry, 3(5), 323-327 (1983-03-01)
A new modification of our detergent technique for the preparation of nuclei for flow cytometric DNA analysis is described. The attainment of low coefficients of variation of the peaks and of quantitative staining of nuclei from different tissues was a
H C Ha et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(19), 11140-11145 (1998-09-16)
The polyamines are small organic cations that are absolutely required for eukaryotic cell growth. Although their growth requirements are well established, the molecular functions of the polyamines are ill-defined. Oxidative damage to DNA by reactive oxygen species is a continual
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