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Merck
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Key Documents

R2156

Sigma-Aldrich

Relaxin-1 human

recombinant, expressed in E. coli, >95% (SDS-PAGE), lyophilized powder

别名:

RLN1, RLXH1, Relaxin 1

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.26

生物源

human

品質等級

重組細胞

expressed in E. coli

化驗

>95% (SDS-PAGE)

形狀

lyophilized powder

分子量

(Contains two disulfide-linked subunits: A chain ~2.8 kDa B chain ~3.3 kDa)

技術

cell culture | mammalian: suitable

適合性

endotoxin tested

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... RLN1(6013)

一般說明

Cell signaling hormone that is prominent in the prostate, and belongs to the insulin superfamily

生化/生理作用

Relaxin 1 may function in regulating blood pressure, controlling heart rate, and releasing oxytocin and vasopressin
Relaxin has been shown to have antifibrotic effects in renal fibroblasts through mechanisms that increase collagenase activity and via TGF-β signaling.

外觀

Lyophilized powder containing BSA

重構

In Phosphate buffered saline solution containing at least 0.1% serum albumin. The concentration should be ≥10 μg/mL

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Rosemary Masterson et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 19(3), 544-552 (2004-02-10)
Renal fibroblasts are important effector cells in tubulointerstitial fibrosis, with experimental antifibrotic strategies focusing on the functional down-regulation of these cells. Several experimental models of fibrosis have provided evidence for the effectiveness of the polypeptide hormone relaxin as a potential

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