P6254

强的松

≥98% (HPLC), powder, anti-inflammatory activity

• 别名: 1-可的松, 17Α,21-二羟基-1,4-孕甾二烯-3,11,20-三酮, 去氢可的松, 强的松
• 经验公式（希尔记法）: C₂₁H₂₆O₅
• CAS号: 53-03-2
• 分子量: 358.43
• Beilstein: 2065301
• EC號碼: 200-160-3
• MDL號碼: MFCD00003608
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24898748
• NACRES: NA.77

属性

• product name: 强的松, ≥98%
• 生物源: synthetic
• 品質等級: 200
• 無菌: non-sterile
• 化驗: ≥98%
• 形狀: powder
• mp: 236-238 °C (lit.)
• 溶解度: chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to light yellow
• 應用: hematology
• 運輸包裝: ambient
• 儲存溫度: room temp
• SMILES 字串: O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1
• InChI: 1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
• InChI 密鑰: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
• 基因資訊: human ... NR3C1(2908)

说明

應用

Prednisone has been used in dimethyl sulfoxide stock suspension to inject into experimental mice and to analyze the effects of glucocorticoid steroid. It has also been used as a test drug, formulated with peanut butter to study the effects of daily administration of MIDD0301, by animal weight, organ weight and haematological analysis.

生化／生理作用

Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activity. It is useful in treating many disease states and has a half-life of 3.4 to 3.8 hours in plasma. Prednisone is metabolized to prednisolone, which is physiologically active.

特點和優勢

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H373
• 防範說明: P260 - P314 - P501
• 危險分類: STOT RE 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges