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Merck

P4997

Sigma-Aldrich

Anti-Potassium Channel KCa3.1 (Intermediate-conductance Ca2+-activated Potassium Channel 4) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

别名:

Anti-IKCa1, Anti-KCNN4, Anti-SK4

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

human, rat, mouse (predicted)

技術

western blot: 1:200

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... KCNN4(3783)
mouse ... Kcnn4(16534)
rat ... Kcnn4(65206)

免疫原

synthetic peptide corresponding to amino acid residues 350-363 of rat KCa3.1. The sequence has 100% homology with human, mouse, and pig.

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)

外觀

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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访问文档库

Spatial separation of endothelial small-and intermediate-conductance calcium-activated potassium channels (KCa) and connexins: possible relationship to vasodilator function?
Sandow SL et al
Journal of Anatomy, 209.5, 689-698 (2006)
Characteristics of Kcnn4 channels in the apical membranes of an intestinal epithelial cell line.
Basalingappa KMet al
American Journal of Physiology: Gastrointestinal and Liver Physiology, 301(5), G905-G911 (2011)
Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice.
Reich EP et al
European Journal of Immunology, 35(4), 1027-1036 (2005)
Phosphatidylserine exposure and calcium-activated potassium efflux in platelets.
Danièle Kerbiriou-Nabias et al.
British journal of haematology, 155(2), 268-270 (2011-04-13)
The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-depenThe Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration.dent neurodegeneration.
Kaushal V et al
The Journal of Neuroscience, 27(1), 234-244 (2007)

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