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P3252

Sigma-Aldrich

6-Phenyl-2-thiouracil

≥95%

别名:

2-Mercapto-6-phenyl pyrimidine-4-ol, 6-Phenylthiouracil, Fenucil

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About This Item

经验公式（希尔记法）:
C10H8N2OS
CAS号:
36822-11-4
分子量:
204.25
EC號碼:
253-227-4
MDL號碼:
MFCD00059166
分類程式碼代碼:
41106305
PubChem物質ID:
24897877
NACRES:
NA.51

生物源

synthetic (organic)

品質等級

100

化驗

≥95%

形狀

powder

溶解度

DMF: 20 mg/mL, clear to slightly hazy, colorless to light yellow

SMILES 字串

Oc1cc(nc(S)n1)-c2ccccc2

InChI

1S/C10H8N2OS/c13-9-6-8(11-10(14)12-9)7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14)

InChI 密鑰

XEKNACRTWJHOCE-UHFFFAOYSA-N

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應用

6-Phenyl-2-thiouracil is a thyreostatic (thyroid hormone) agent that may be used as a reference material in thyreostatic drug separation and detection technologies such as capillary electrophoresis, HPLC, or gas chromatography.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Sigma-Aldrich

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S Abuín et al.
Analytica chimica acta, 617(1-2), 184-191 (2008-05-20)
A method based on ultra-performance liquid chromatography-electrospray ionisation-tandem mass spectrometry for the determination of six thyreostatic drugs in thyroid tissue has been optimised and validated in accordance with the Decision 2002/657/EC. Samples are extracted with methanol and the extracts cleaned-up
Dexian Kong et al.
Electrophoresis, 30(19), 3489-3495 (2009-09-04)
A simple, rapid, reproducible and sensitive method based on CE with electrochemical detector was developed for the simultaneous determination of five thyreostatics including 2-thiouracil (TU), 6-methyl-2-thiouracil (MTU), 6-propyl-2-thiouracil (PTU), 6-phenyl-2-thiouracil (PhTU) and methimazole (TAP) in animal feeds. A home-made wall-jet
Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.
M Baba et al.
Antiviral research, 17(4), 245-264 (1992-04-01)
R Schilt et al.
Journal of chromatography, 489(1), 127-137 (1989-04-07)
Methods are described for the screening and confirmation of residues of the thyreostatics thiouracil, methylthiouracil and propylthiouracil in urine samples of cattle at levels down to 25 micrograms/l. After a selective preconcentration of the thiol-containing thyreostatics on a mercurated affinity
X Huang et al.
Journal of molecular and cellular cardiology, 32(12), 2221-2228 (2000-12-13)
Two main troponin I genes, cardiac (cTnI) and slow skeletal (ssTnI), are expressed in the mammalian heart under the control of a developmentally regulated program. ssTnI is expressed first in embryonic and fetal heart, and is then downregulated by an
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