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Merck

P2745

Sigma-Aldrich

蛋白磷酸酶抑制剂 1 人

别名:

抑制剂 1 人

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.77

生物源

human

品質等級

重組細胞

expressed in E. coli

化驗

>95% (SDS-PAGE)

形狀

solution

分子量

~31 kDa
apparent mol wt ~27 kDa

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

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應用

此蛋白磷酸酶抑制剂1适合用作底物,以鉴定调节蛋白磷酸酶抑制剂1活性的新型磷酸酶和激酶。该产品也适用于亲和力敲低结合研究。蛋白磷酸酶抑制剂1人已被用作蔗糖细胞裂解缓冲液中的一种成分。在药理学干预研究中,在腹膜前或腹膜内注射之前,它还被用于对小鼠进行腹膜内注射。

生化/生理作用

该酶作为磷酸化酶磷酸酶的抑制剂密切参与糖原代谢,负责将磷酸化酶 b转换为磷酸化酶 a。仅在cAMP依赖性蛋白激酶磷酸化时,才会激活抑制作用。

外觀

以pH 7.0,含 50mM Tris-HCl、0.1 mM PMSF、14 mM 2-巯基乙醇和10%甘油的溶液形式提供

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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