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品質等級
化驗
≥97% (HPLC)
形狀
powder
顏色
yellow
溶解度
1 M NaOH: 1 mg/mL, clear, yellow-orange
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4
InChI
1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1
InChI 密鑰
PLAPMLGJVGLZOV-VPRICQMDSA-N
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一般說明
荭草素(ORI)是一种木犀草素衍生物,也是水溶性8-C糖苷膳食黄酮。它的化学结构中有一个酮基、两个醚基和苯基。荭草素来源于多种药用植物,如O Ocimum sanctum(圣罗勒)、Phyllostachys类(竹叶)、Passiflora 类、Trollius类等。
應用
荭草素已被用于:
- 作为抗炎症和抗增殖剂用于测试其对大鼠模型中1,2-二甲基肼(DMH)引起的结肠直肠癌的保护作用
- 作为类黄酮用于研究其对抗霉素A引起的鼠C2C12骨骼肌细胞中线粒体功能障碍的保护作用
- 作为流感病毒聚合酶PA亚单位的潜在核酸内切酶抑制剂
生化/生理作用
荭草素对于过氧化氢引起的SH-SY5Y神经母细胞具有神经保护作用。 它具有抗氧化、抗炎症、抗老化、抗抑郁剂、血管舒张和心脏保护作用。
黄酮苷存在于阿萨伊树、金梅草和西番莲中。抗病毒、抗菌和抗氧化剂。具有防辐射活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
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The current study investigated the physiological effects of flavonoids found in daily consumed rooibos tea, aspalathin, isoorientin, and orientin on improving processes involved in mitochondrial function in C2C12 myotubes. To achieve this, C2C12 myotubes were exposed to a mitochondrial channel
Acta neurologica Belgica, 92(1), 30-35 (1992-01-01)
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Planta medica, 77(10), 984-991 (2011-02-02)
In this study, we provide new evidence that orientin from bamboo leaves (Phyllostachys nigra) protect H9c2 cardiomyocytes against ischemia/reperfusion (I/R) injury through the mitochondrial apoptotic pathway. A previous work has identified that orientin could protect myocardium against ischemia/reperfusion injury. Mitochondria
Biomedical chromatography : BMC, 22(10), 1130-1136 (2008-07-25)
A selective and sensitive reversed-phase high-performance liquid chromatography method was developed and validated for the simultaneous determination of orientin-2''-O-beta-L-galactopyranosyl (OGA), orientin and vitexin in rat plasma. Blood samples were collected via the fossa orbitalis vein at time intervals after intravenous
Basic & clinical pharmacology & toxicology, 99(5), 365-373 (2006-11-02)
Rooibos tea has been widely used for abdominal spasm and diarrhoea. The aim of the present study was to explore the possible mechanism for its use in such ailments. Its aqueous extract (RT) at 0.3-10 mg/ml produced relaxation of spontaneous
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