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Merck

O2751

Sigma-Aldrich

草氨酸钠

≥98%

别名:

氨基氧乙酸 钠盐, 草氨酸 钠盐, 草酸单酰胺 钠盐

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About This Item

线性分子式:
NH2COCOONa
CAS号:
分子量:
111.03
Beilstein:
6538153
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

化驗

≥98%

形狀

powder

mp

300 °C

溶解度

water: 50 mg/mL, clear, colorless

SMILES 字串

[Na+].NC(=O)C([O-])=O

InChI

1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1

InChI 密鑰

RQVZIJIQDCGIKI-UHFFFAOYSA-M

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應用

草案酸钠用于:
  • 流动注射分析变量
  • 体外血管新生实验
  • 确认硬脂酸在乳糖脱氢酶介导乳糖生产中的刺激作用

生化/生理作用

丙酮酸结构类似物,抑制L(+)-乳酸脱氢酶,使得整个糖异生途径脱轨。乳酸脱氢酶结合研究;抑制线粒体丙酮酸代谢机制
草氨酸钠影响脂肪酸代谢。可用于治疗糖尿病。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Joshua Marshall Thornburg et al.
Breast cancer research : BCR, 10(5), R84-R84 (2008-10-17)
Glycolysis is increased in breast adenocarcinoma cells relative to adjacent normal cells in order to produce the ATP and anabolic precursors required for survival, growth and invasion. Glycolysis also serves as a key source of the reduced form of cytoplasmic
Role of ATP during the initiation of microvascularization: acceleration of an autocrine sensing mechanism facilitating chemotaxis by inorganic polyphosphate
Muller Werner EG, et al.
The Biochemical Journal, 475(20), 3255-3273 (2018)
Otic Antiinfectives-Advances in Research and Application, 56-56 (2013)
Huo-Lei Peng et al.
Photochemistry and photobiology, 93(5), 1193-1203 (2017-04-10)
Fluorescence of Reduced Nicotinamide Adenine Dinucleotide (NADH) is extensively employed in studies of oxidoreductases. A substantial amount of static and kinetic work has focused on the binding of pyruvate or substrate mimic oxamate to the binary complex of lactate dehydrogenase
Black Inventors: Crafting Over 200 Years of Success, 5(20), 13092-13092 (2012)

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We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

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