N6803

Nystatin water soluble

powder, suitable for cell culture

• 别名: Nystatin Solution
• 分類程式碼代碼: 12352207
• NACRES: NA.76

属性

• product name: Nystatin water soluble, suitable for cell culture
• 生物源: synthetic
• 形狀: powder
• 分子量: 1029.23 g/mol
• 技術: cell culture | mammalian: suitable
• 溶解度: 100 mg/mL
• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

Nystatin is a polyene, broad-spectrum antibiotic. It can modify the microstructure of lipid rafts and sequestrate cholesterol present on the cell membrane of eukaryotes. Thus, nystatin can modulate immune responses. This is carried out through cytokine signaling, activation of lymphocytes and pathogen recognition.
Molecular Formula: C₅₁H₈₄N₂O₁₉
Molecular Weight: 1029.23

Nystatin water soluble is a Nystatin derivate with fungistatic and fungicidal activity in resemblance to Nystatin. However, as opposed to the poor solubility of Nystatin the water soluble derivate can be dissolved in concentration of up to 100mg/ml. Nystatin binds to ergosterol which increases cell membrane permeability in sensitive fungi. Nystatin is mainly clinically active against Candida species. However, it is also reported to be effective against Aspergillus, Coccidioides immitis, Cryptococcus neoformans, Histoplasma capsulatum, Blastomyces dermatidis, and other yeasts and fungi. Nystatin has also been used to enrich mutants by negative selection in yeasts. The minimum inhibitory concentration (MIC) of Nystatin to Saccharomyces cerevisiae was reported to be 3μg/ml while for clinical isolates of Candida albicans the MIC was reported to be 4-16μg/ml.

其他說明

Technical data

• Nystatin water soluble is a fully solubilized powder of Nystatin with potency of ≥2000 units/mg according to USP standard.
• Nystatin water soluble is 0.2μm filtered and endotoxin free.
• The suggest working concentration of Nystatin water soluble is 100 units/ml.
• It is recommended to store solutions of Nystatin water soluble in the dark.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable