推荐产品
生物源
mouse
品質等級
重組細胞
expressed in NSO cells
化驗
>95% (SDS-PAGE)
形狀
lyophilized powder
分子量
55-60 kDa by SDS-PAGE (reducing)
calculated mol wt 50 kDa
包裝
pkg of 50 μg
雜質
endotoxin, tested
UniProt登錄號
儲存溫度
−20°C
基因資訊
mouse ... Nog(18121)
生化／生理作用
Binds and blocks the acitivity of bone morphogenetic proteins (BMPs). Mature mouse noggin shares 99% and 83% sequence identity with human and Xenopus noggin, respectively.
外觀
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
分析報告
The biological activity is measured by its ability to inhibit recombinant human BMP-4 induced alkaline phosphatase activity in ATDC5 cells.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
D A Lim et al.
Neuron, 28(3), 713-726 (2001-02-13)
Large numbers of new neurons are born continuously in the adult subventricular zone (SVZ). The molecular niche of SVZ stem cells is poorly understood. Here, we show that the bone morphogenetic protein (BMP) antagonist Noggin is expressed by ependymal cells
Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice.
Wu XB
The Journal of Clinical Investigation (2003)
The expression patterns of gremlin 1 and noggin in normal adult and tumor tissues.
Laurila R
International Journal of Clinical and Experimental Pathology (2013)
A H Reddi
Arthritis research, 3(1), 1-5 (2001-02-15)
This commentary is a concise discussion of the interactions between bone morphogenetic proteins (BMPs) and their binding proteins in bone and cartilage morphogenesis. BMPs are a family of growth and differentiation factors, and they act on mesenchymal cells to induce
Human disease-causing NOG missense mutations: effects on noggin secretion, dimer formation, and bone morphogenetic protein binding.
Marcelino J
Proceedings of the National Academy of Sciences of the USA (2001)
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