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Merck

MAK068

Sigma-Aldrich

MPO活性检测试剂盒(比色法)

sufficient for 100 colorimetric tests

别名:

髓过氧化物酶比色活性检测试剂盒

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84

用途

sufficient for 100 colorimetric tests

檢測方法

colorimetric

相關疾病

cancer; cardiovascular diseases; hematological disorder

儲存溫度

−20°C

基因資訊

human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)

一般說明

髓过氧化物酶(MPO)是一种含血红素的酶,催化氢过氧化物酶介导的卤离子氧化为次氯酸。髓过氧化物酶是一种在中性粒细胞中高度表达的溶酶体蛋白,其在由中性粒细胞刺激引起的抗微生物作用中起作用。髓过氧化物酶的作用也可能有助于心血管疾病的发生和发病。

應用

髓过氧化物酶比色活性测定试剂盒已用于测定样品中髓过氧化物酶的活性。

特點和優勢

兼容高通量处理系统。

適合性

适用于组织、细胞、血清和白细胞等生物样本中髓过氧化物酶 (MPO) 的测定

原則

在该测定中,髓过氧化物酶催化次氯酸的形成,次氯酸与牛磺酸反应形成牛磺酸氯胺。牛磺酸氯胺与发色团 TNB 反应,形成无色产物 DTNB。一个单位的髓过氧化物酶活性定义为在 25℃ 下,每分钟水解底物并产生牛磺酸氯胺以消耗 1.0 μmole TNB的酶量。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

閃點(°F)

188.6 °F

閃點(°C)

87 °C


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