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MAK037

Sigma-Aldrich

NAD/NADH 定量试剂盒

sufficient for 100 colorimetric tests

别名:

NAD/NADH检测试剂盒

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

用途

sufficient for 100 colorimetric tests

檢測方法

colorimetric

相關疾病

cancer

儲存溫度

−20°C

一般說明

烟酰胺腺嘌呤二核苷酸(NAD)是一种参与多种氧化还原反应的酶辅因子。NAD作为电子载体，在氧化(NAD)和还原(NADH)形式之间循环。NAD除了在氧化还原反应中发挥作用外，在ADP(二磷酸腺苷)-核糖基化反应和作为去乙酰化酶的底物中也发挥着关键作用。

應用

NAD/NADH定量试剂盒已可用于，当存在曲美他嗪时，SIRT1(去乙酰化酶1)活性(与缺血再灌注损伤相关)对NAD+/NADH定量的影响。

適合性

适用于动物组织(肝、肾等)、细胞培养(贴壁细胞或悬浮细胞)、血清或尿液中NADH和NAD的检测。

原則

NAD/NADH定量试剂盒为敏感检测细胞内核苷酸、NAD(烟酰胺腺嘌呤二核苷酸)和NADH及它们的比值提供了一种方便的工具，无需从样品中纯化NAD/NADH。该试剂盒针对NAD和NADH，不检测NADP或NADPH。NADt(NAD和NADH)或NADH在比色法(450 nm)中定量。

相關產品

产品编号
说明
价格

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

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Mammalian sirtuins?emerging roles in physiology, aging, and calorie restriction.
Haigis M C and Leonard P G
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Frédérique Moyrand et al.
Eukaryotic cell, 7(12), 2069-2077 (2008-09-30)
The genome of the basidiomycete pathogenic yeast Cryptococcus neoformans carries two UDP-glucose epimerase genes (UGE1 and UGE2). UGE2 maps within a galactose cluster composed of a galactokinase homologue gene and a galactose-1-phosphate uridylyltransferase. This clustered organization of the GAL genes
Deepanwita Banerjee et al.
BMC systems biology, 11(1), 51-51 (2017-04-28)
The leading edge of the global problem of antibiotic resistance necessitates novel therapeutic strategies. This study develops a novel systems biology driven approach for killing antibiotic resistant pathogens using benign metabolites. Controlled laboratory evolutions established chloramphenicol and streptomycin resistant pathogens
Andrea M Lencina et al.
mBio, 9(4) (2018-07-05)
The opportunistic pathogen Streptococcus agalactiae is the major cause of meningitis and sepsis in a newborn's first week, as well as a considerable cause of pneumonia, urinary tract infections, and sepsis in immunocompromised adults. This pathogen respires aerobically if heme
Haiping Wang et al.
Nature immunology, 21(3), 298-308 (2020-02-19)
Depleting regulatory T cells (Treg cells) to counteract immunosuppressive features of the tumor microenvironment (TME) is an attractive strategy for cancer treatment; however, autoimmunity due to systemic impairment of their suppressive function limits its therapeutic potential. Elucidating approaches that specifically
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