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Merck

M6045

Sigma-Aldrich

2-甲基-4-异噻唑啉-3-酮 盐酸盐

≥99%

别名:

MIT, 甲基异噻唑啉酮 盐酸盐

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About This Item

经验公式(希尔记法):
C4H5NOS · HCl
CAS号:
分子量:
151.61
Beilstein:
3993054
EC號碼:
MDL號碼:
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.76

品質等級

化驗

≥99%

作用方式

protein synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

Cl[H].CN1SC=CC1=O

InChI

1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H

InChI 密鑰

SJXPQSRCFCPWQQ-UHFFFAOYSA-N

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一般說明

2-甲基-4-异噻唑啉-3-酮盐酸盐(MIT,甲基异噻唑啉酮)是合成异噻唑啉酮的衍生物。

應用

甲基异噻唑啉酮(MIT)已用于:
  • 研究MIT作为细胞毒性物质,对支气管上皮细胞(BEAS-2B)和的影响,及在凋亡性细胞死亡中的作用
  • 研究酪氨酸磷酸化对神经轴突和树突发育过程中粘着斑激酶(FAK)活性的影响

生化/生理作用

2-甲基-4-异噻唑啉-3-酮盐酸盐(MIT)是皮肤致敏物,会引起接触性皮炎和过敏。它在化妆品行业中广泛用作防腐剂。甲基异噻唑啉酮是一种神经毒素,过久暴露可能会引起神经元细胞死亡和神经突生长抑制。

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1

安全危害

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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