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Merck

M4773

Sigma-Aldrich

间羟胺 (+)-酒石酸氢盐

别名:

阿拉明 酒石酸氢盐

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About This Item

经验公式(希尔记法):
C9H13NO2 · C4H6O6
CAS号:
分子量:
317.29
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

起源

Merck & Co., Inc., Kenilworth, NJ, U.S.

SMILES 字串

O[C@H]([C@@H](O)C(O)=O)C(O)=O.C[C@H](N)[C@H](O)c1cccc(O)c1

InChI

1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;1-,2-/m01/s1

InChI 密鑰

VENXSELNXQXCNT-IJYXXVHRSA-N

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應用

Metaraminol (+)-bitartrate salt has been used to study the effects of adrenergic agonists in the mouse model of endometriosis.

生化/生理作用

α-adrenoceptor agonist.
Metaraminol may serve as a false sympathetic transmitter. It is a mixed α - and β-adrenergic agonist.

特點和優勢

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Studies on the interrelationship between the syntheses of noradrenaline and metaraminol
Johnson GE and Pugsley TA
British Journal of Pharmacology, 39(1), 167-174 (1970)
J Tanaka et al.
Experimental neurology, 152(2), 303-306 (1998-08-26)
To verify whether noradrenergic inputs to the subfornical organ (SFO) are involved in the control system of arterial pressure, we investigated the effects of blood pressure changes on noradrealine (NA) release in the SFO and its surrounding sites using microdialysis
Einly Lim et al.
Artificial organs, 36(5), E110-E124 (2012-04-12)
A heart-pump interaction model has been developed based on animal experimental measurements obtained with a rotary blood pump in situ. Five canine experiments were performed to investigate the interaction between the cardiovascular system and the implantable rotary blood pump over
Impact of admixture time and diluent order on metaraminol concentration.
J N Darvall et al.
Anaesthesia and intensive care, 37(5), 859-860 (2009-09-25)
Marilyn P Law et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(8), 1269-1276 (2010-08-04)
Dysfunction of the sympathetic nervous system underlies many cardiac diseases and can be assessed by molecular imaging using PET in humans. Small-animal PET should enable noninvasive quantitation of the sympathetic nervous system in mouse models of human disease. For mice

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