推荐产品
生物源
Escherichia coli (O55:B5)
品質等級
形狀
lyophilized powder
純化經由
ion-exchange chromatography
雜質
<1% Protein
<1% RNA
顏色
white to yellow cast
溶解度
water: soluble
運輸包裝
ambient
儲存溫度
2-8°C
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相关类别
一般說明
本产品是从大肠杆菌血清型 O55：B5 中提取而来，并通过离子交换进行了纯化。源菌株是 CDC 1644-70。LPS O55：B5 已用于刺激人腹膜巨噬细胞，以 1 ng/mL 的浓度，并以 1-100 ng/mL 的浓度刺激马腹膜巨噬细胞。
應用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征组分。脂多糖及其脂质 A 部分通过 Toll 样受体 4（TLR4）刺激先天免疫系统的细胞，Toll 样受体 4是 Toll 样受体蛋白家族的成员，其识别常见的病原体相关分子模式（PAMP）。
生化／生理作用
脂多糖（LPS）位于膜的外层，并且在非包膜菌株中暴露在细胞表面上。它们有助于外膜的完整性，并保护细胞免受胆汁盐和亲脂性抗生素的影响。
準備報告
产物可溶于水（5mg/ml）或细胞培养基（1mg/ml），产生模糊的淡黄色溶液。在涡旋，并升温至 70-80 oC 后，在含水盐水中得到更浓缩但仍然浑浊的溶液（20 mg/ml）。脂多糖是在每种溶剂中形成胶束的分子。在水和磷酸盐缓冲盐水中观察到浑浊的溶液。有机溶剂不能提供更澄清的溶液。甲醇产生具有漂浮物的浑浊悬浮液，而水产生均匀浑浊溶液。
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Arij Faksh et al.
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Li Liu et al.
Journal of cellular and molecular medicine, 19(12), 2728-2740 (2015-08-21)
It remains unclear whether and how cardiomyocytes contribute to the inflammation in chronic heart failure (CHF). We recently reviewed the capacity of cardiomyocytes to initiate inflammation, by means of expressing certain immune receptors such as toll-like receptors (TLRs) that respond
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Atherosclerosis is a chronic inflammatory disease that has its origins in early life. Postnatal inflammation exacerbates atherosclerosis, but the possible effect of intrauterine inflammation is largely unexplored. Exposure to inflammation in utero is common, especially in infants born preterm, who
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