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Key Documents

L2262

Sigma-Aldrich

脂多糖 来源于肠沙门氏菌 肠道血清型

purified by gel-filtration chromatography

别名:

LPS(脂多糖)

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About This Item

MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

Salmonella enterica (Serotype typhimurium)

品質等級

形狀

lyophilized powder

純化經由

gel-filtration chromatography

雜質

<1% Protein

顏色

white to faint yellow

溶解度

water: 0.90-1.10 mg/mL, hazy to turbid, colorless to faintly yellow

運輸包裝

ambient

儲存溫度

2-8°C

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一般說明

本品从鼠伤寒沙门氏菌中提取,经凝胶过滤纯化。来源菌株为 ATCC 7823。

應用

脂多糖(LPS)是革兰氏阴性细菌细胞壁的特征组分。LPS及其脂质A部分通过Toll样受体4(TLR4)刺激先天免疫系统的细胞,Toll样受体 4是Toll样受体蛋白家族的成员,其识别常见的病原体相关分子模式(PAMP)。

生化/生理作用

脂多糖 (LPS) 定位于膜的外层,在无荚膜的菌株中暴露于细胞表面。它们有助于外膜的完整性,并保护细胞免受胆盐和亲脂性抗生素的操作。

準備報告

本品可溶于水 (5 mg/mL) 或细胞培养基 (1 mg/mL),得到淡黄色浑浊溶液。涡旋并加热至 70-80 oC 后,在盐水中获得了更浓缩但仍浑浊的溶液 (20 mg/mL)。脂多糖是在每种溶剂中形成胶束的分子。在水和磷酸盐缓冲盐水中观察到浑浊溶液。有机溶剂不能提供更清晰的溶液。甲醇产生浑浊的带有悬浮物的混悬液,而水产生均匀的浑浊溶液。

其他說明

为了全面了解我们针对客户研究提供的各种脂多糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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