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一般說明
IgG 有 4 种同种型 IgG1、IgG2、IgG3 和 IgG4。它包含 4 个多肽链，由 2 条相同的 50 kDa γ 重（H）链和 2 条相同的 25 kDa κ或 λ 轻（L）链组成，它们通过链间二硫键连接。
應用
纯化的 IgG 可用作各种免疫测定中的参考抗原、标准品、封闭剂或包被蛋白，包括 ELISA、斑点免疫结合、蛋白免疫印迹、免疫扩散、免疫沉淀和免疫电泳等。其他应用包括作为制备免疫原和固相免疫吸附剂的起始材料。
生化／生理作用
IgG 介导经胎盘转运并参与二次免疫反应。IgG 激活补体系统的经典途径。它中和病毒颗粒和毒素。IgG 在抗体依赖性细胞介导的细胞毒性（ADCC）和吞噬作用中起关键作用。它可能与过敏有关。它具有最长的血清半衰期。
IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌，存在于血液和细胞外液中，可防止细菌、真菌和病毒引起的感染。母体IgG可通过胎盘转移至胎儿，胎盘对新生儿免疫防御感染至关重要。
分析報告
蛋白质浓度应在重组后通过 280 nm 处的吸光度（E1%/280 = 14）测定。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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