一般說明
IgG 抗体亚型是免疫系统中含量最高的血清免疫球蛋白。由B细胞分泌,存在于血液和细胞外液中,免疫球蛋白有两条重链(H)和两条轻链(L),通过二硫键连接。 每条轻链含一个N-末端可变区和一个C-末端恒定区。重链有一个N-末端可变区和三个或四个(CH1-CH4)C-末端恒定区。IgG 的四种类型分别为IgG1、IgG2、IgG3和IgG4。IgG抗体提供保护作用,防止细菌、真菌和病毒引起的感染。母体IgG通过胎盘传递给胎儿,对新生儿抵抗感染的免疫防御能力至关重要。大鼠IgG 由分级分离和离子交换层析从混合的正常大鼠血清中纯化得到。
應用
大鼠血清IgG用于:
- 免疫标记
- 流式细胞术
- 酶联免疫吸附试验
- 作为对照品,用于中性粒细胞耗竭试验
生化/生理作用
IgG抗体具有巨大的治疗潜力,其可结晶片段(Fc)区域有助于研发治疗性抗体。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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Sigma’s Imprint RNA Immunoprecipitation Kit was used to copurify human argonaute 2 (Ago2)-associated RNAs from HeLa cells. MicroRNAs reverse transcribed and quantitating using Mysticq reagents.
实验方案
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