I134

L-N⁵-（1-氨基乙基）鸟氨酸 盐酸盐

≥95% (HPLC)

• 别名: L-NIO hydrochloride, L-Ornithine ψ-acetamidine hydrochloride
• 经验公式（希尔记法）: C₇H₁₅N₃O₂ · xHCl
• CAS号: 852173-80-9
• 分子量: 173.21 (free base basis)
• MDL號碼: MFCD00153817
• 分類程式碼代碼: 12352204
• PubChem物質ID: 329815348
• NACRES: NA.26

属性

• 化驗: ≥95% (HPLC)
• 形狀: powder
• 分子量: calculated mol wt 173.22 g/mol
• 儲存條件: desiccated; under inert gas
• 顏色: white to beige
• 溶解度: H₂O: 2 mg/mL, clear (warmed)
• 儲存溫度: −20°C
• SMILES 字串: CC(NCCC[C@H](N)C(O)=O)=N.[H]Cl
• InChI: 1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1
• InChI 密鑰: JIBZSGQTCBWUKL-RGMNGODLSA-N

说明

應用

L-N⁵-(1-Iminoethyl) ornithine hydrochloride has been used to study the effects of the cytotoxic drug paclitaxel and carbachol (a cholinergic agonist) to induce death in breast tumor MCF-7 cells and the role of nitric oxide synthase (NOS) in this effect. It has also been used to study its effects on pulmonary arterial responses to sufentanil in the feline pulmonary vascular bed.

生化／生理作用

A potent irreversible inhibitor of nitric oxide synthase.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves