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Merck

H4535

Sigma-Aldrich

Anti-Heme Oxygenase-1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-HO-1, Anti-HSP32

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~32 kDa

物種活性

rat, mouse

技術

immunohistochemistry: 5 μg/mL
immunoprecipitation (IP): 10-20 μg/mL
western blot: 0.5-2 μg/mL

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... HMOX1(3162)
mouse ... Hmox1(15368)
rat ... Hmox1(24451)

免疫原

Synthetic peptide surrounding amino acids near the N-terminus of human HO-1.

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)

外觀

Solution in phosphate buffered saline containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Lorenzo L F Glorie et al.
American journal of physiology. Renal physiology, 303(5), F681-F688 (2012-06-22)
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase which modulates the function of its substrates, among which are insulin-releasing incretins. DPP4 inhibitors are currently used to improve glucose tolerance in type 2 diabetes patients. Inhibition of DPP4 exhibits protective effects on
Megan A Mahlke et al.
Pathobiology of aging & age related diseases, 1 (2011-01-01)
The anti-tumor effects of calorie restriction (CR) and the possible underlying mechanisms were investigated using ethylnitrosourea (ENU)-induced glioma in rats. ENU was given transplacentally at gestational day 15, and male offspring were used in this experiment. The brain from 4-
Mitsutoshi Tsukimoto et al.
Journal of radiation research, 51(3), 349-353 (2010-04-23)
The transcription factor nuclear erythroid-derived 2-related factor 2 (Nrf2) regulates expression of genes encoding antioxidant proteins involved in cellular redox homeostasis, while gamma-ray irradiation is known to induce reactive oxygen species in vivo. Although activation of Nrf2 by various stresses
Qunli Cui et al.
Molecular medicine reports, 13(2), 1381-1388 (2015-12-10)
Parkinson's disease (PD) is an age-related complex neurodegenerative disease that affects ≤ 80% of dopaminergic neurons in the substantia nigra pars compacta (SNpc). It has previously been suggested that mitochondrial dysfunction, oxidative stress and oxidative damage underlie the pathogenesis of
Abdulla K Salahudeen et al.
Transplantation, 91(2), 176-182 (2010-11-16)
Kidneys from brain-dead donors are cold preserved until transplanted. However, prolonged cold storage can contribute to allograft failure. Studies suggest that donor preconditioning with dopaminergics may reduce cold-ischemic transplant injury, but whether heme oxygenase (HO)-1 induction is an underlying mechanism

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