推荐产品
生物源
chicken
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
rat, human, mouse
製造商／商標名
Genway 15-288-20083F
技術
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... IGHG1(3500)
免疫原
IgG Fc 人天然蛋白。
應用
抗人 IgG（Fc 特异性）抗体（鸡来源）适用于蛋白质印迹分析（1：500 稀释），也适用于组织或细胞染色（1：200 稀释）。
生化／生理作用
Ig γ-1链C区是人IGHG1基因编码的蛋白。Ig γ-1链C区存在于人胰腺癌组织中，在邻近的非癌组织中表达极低。阻断IGHG1可延缓肿瘤生长、提高生存率。它在胰腺癌细胞中的存在可能是参与肿瘤细胞增殖和免疫逃避机制的重要因素。IGHG1与前列腺癌相关，可抑制细胞活力，从而导致细胞凋亡。它是前列腺癌基因治疗的潜在靶点。
外觀
含有 0.02％ 叠氮化钠的磷酸盐缓冲盐水溶液。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
其他客户在看
Judith Blaine
Methods in molecular biology (Clifton, N.J.), 2224, 123-132 (2021-02-20)
Proteinuria is a widely used marker of renal disease and is strongly associated with renal and cardiovascular outcomes. The molecular mechanisms underlying filtration of serum proteins through the glomerular filtration barrier (GFB) remain to be determined. Since the GFB is
Xiaoyan Li et al.
Pancreas, 40(5), 753-761 (2011-06-10)
To investigate the expression of Igγ-1 chain C region (IGHG1) in human pancreatic carcinomas and determine the biological function of IGHG1 expression in immune evasion mechanisms. Comparative proteomic analysis was used to detect the differential expression of IGHG1 in human
Bin Pan et al.
Molecular biology reports, 40(1), 27-33 (2012-11-03)
To investigate the immunoglobulin G (IgG) expression in prostate cancer cell lines and explore the effects of IGHG1 gene knockdown on PC3 cell growth and apoptosis. Flow cytometry, qPCR and western blot were used to demonstrate IgG expression in prostate
James Dylewski et al.
PloS one, 14(2), e0209732-e0209732 (2019-02-28)
Proteinuria is strongly associated with kidney disease progression but the mechanisms underlying podocyte handling of serum proteins such as albumin and IgG remain to be elucidated. We have previously shown that albumin and IgG are transcytosed by podocytes in vitro.
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