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Merck

G2299

SAFC

L -氧化谷胱甘肽

制药生产

别名:

GSSG, 氧化谷胱甘肽

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About This Item

经验公式(希尔记法):
C20H32N6O12S2
CAS号:
分子量:
612.63
Beilstein:
1718700
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.21

生物源

synthetic

品質等級

形狀

powder

溶解度

H2O: 10 mg/mL, clear, colorless

適合性

suitable for manufacturing use

儲存溫度

2-8°C

SMILES 字串

N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChI 密鑰

YPZRWBKMTBYPTK-BJDJZHNGSA-N

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Amino Acid Sequence

Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]

一般說明

我们的SAFC®高质量原材料产品组合用于生物制药工艺,可通过严苛的质控程序并提供配套文档和技术专长,帮助客户满足 M-Clarity 计划规定的要求。

M-Clarity 计划

我们全面的下游工艺化学品产品组合不仅为生物制药制造商提供生产传统和新型治疗制剂所需的优质原材料,还可帮助他们加速产品上市并简化监管问题。从低风险应用的非 GMP 等级,到高风险应用的 IPEC-PQG GMP标准,我们的产品可满足您的所有制造需求。

法律資訊

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

相關產品

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Alzheimer's disease (AD), characterized by progressive loss of memory, language, reasoning and other cognitive functions, including dementia, is characterized pathologically by the presence of senile plaques, neurofibrillary tangles and synapse loss. Increased oxidative/nitrosative stress, decreased antioxidants, mitochondrial damage and other
Vladimir L Kolossov et al.
Experimental biology and medicine (Maywood, N.J.), 239(4), 394-403 (2014-03-04)
The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, the underlying mechanisms behind this relationship are
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Blood, 124(10), 1626-1636 (2014-07-10)
The aim of this study was to assess the efficiency of p53 reactivation and induction of massive apoptosis (PRIMA-1(Met)) in inducing myeloma cell death, using 27 human myeloma cell lines (HMCLs) and 23 primary samples. Measuring the lethal dose (LD50)
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