無菌
non-sterile
品質等級
形狀
lyophilized powder
標籤範圍
~30 mol steroid per mol BSA
溶解度
phosphate buffer: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
運輸包裝
ambient
儲存溫度
2-8°C
一般說明
β-Estradiol 6-(O-carboxymethyl)oxime: BSA is an estradiol conjugate and is membrane-impermeable. BSA is linked to the estradiol at position 6 to form the β-estradiol 6-(O-carboxymethyl) oxime: BSA conjugate.
應用
β-Estradiol 6-(O-carboxymethyl)oxime: BSA has been used:
- to test its effect on the N-methyl-D-aspartate receptor (NMDAR) currents in female dorsal root ganglion (DRG) neurons
- to coat microplates for the detection of plasma 17β-Estradiol levels using indirect enzyme-linked immunosorbent assay (ELISA)
- to test its effect on MutL homolog 1 in colorectal cancer lines
生化／生理作用
β-Estradiol 6-(O-carboxymethyl)oxime: BSA mimics estrogen and favors amyloid precursor protein α (sAPPα) secretion in vitro studies with primary rat cortical neurons. It also stimulates mitogen-activated protein kinase (MAPK) activity in human umbilical vein endothelial cells
訊號詞
Warning
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
Claudio R F Marinho et al.
PloS one, 4(5), e5630-e5630 (2009-05-23)
Pregnancy-associated malaria (PAM) is associated with placenta pathology and poor pregnancy outcome but the mechanisms that control the malaria parasite expansion in pregnancy are still poorly understood and not amenable for study in human subjects. Here, we used a set
Sex-dependent differences in the activity and modulation of N-methyl-d-aspartic acid receptors in rat dorsal root ganglia neurons.
McRoberts, et al.
Neuroscience, 148, 1015-1020 (2018)
Yu-Jie Lai et al.
Journal of molecular neuroscience : MN, 61(3), 436-448 (2017-02-06)
Estrogen exerts multiple actions in the brain and is an important neuroprotective factor in a number of neuronal disorders. However, the underlying mechanism remains unknown. Studies demonstrate that ubiquitin-conjugating enzyme 9 (ubc9) has an integral role in synaptic plasticity and
Jun-Yu Lu et al.
Oncotarget, 8(24), 38767-38779 (2017-04-14)
Epidemiological data demonstrated that hormone replace treatment has protective effect against colorectal cancer (CRC). Our previous studies showed that this effect may be associated with DNA mismatch repair. This study aims to investigate the mechanism of estrogen induction of MLH1
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