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化驗
~96% (HPLC)
品質等級
儲存溫度
−20°C
SMILES 字串
[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)C3=CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
InChI
1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1
InChI 密鑰
QSVJYFLQYMVBDR-CMNOFMQQSA-N
一般說明
Ergosta-5,7,9（11）,22-tetraen-3β-ol 是麦角固醇的类似物。它由甾体环系统中的三个共轭双键组成。Ergosta-5,7,9（11）,22-tetraen-3β-ol 具有抗炎特性。它用作胆固醇报告物。
應用
Ergosta-5,7,9（11）,22-tetraen-3β-ol 已用于检查卵磷脂：胆固醇酰基转移酶（LCAT）的酰基转移酶活性。它也已经用于脂质体的制备。
荧光胆固醇类似物，可用作膜研究的探针。
訊號詞
Warning
危險聲明
危險分類
Carc. 2 - STOT RE 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Alexander G Georgiev et al.
Traffic (Copenhagen, Denmark), 12(10), 1341-1355 (2011-06-22)
Sterol transport between the endoplasmic reticulum (ER) and plasma membrane (PM) occurs by an ATP-dependent, non-vesicular mechanism that is presumed to require sterol transport proteins (STPs). In Saccharomyces cerevisiae, homologs of the mammalian oxysterol-binding protein (Osh1-7) have been proposed to
Fluorescent sterols: probe molecules of membrane structure and function.
F Schroeder
Progress in lipid research, 23(2), 97-113 (1984-01-01)
Fischer, R.T., et al.
J. Biol. Physics, 13, 13-13 (1985)
Tim P Levine
The Journal of cell biology, 195(6), 927-929 (2011-12-14)
A new study in this issue (De Saint-Jean et al. 2011. J. Cell Biol. http://dx.doi.org/jcb.201104062) reveals that the sterol transfer protein Osh4p can also transport the signaling phospholipid phosphatidylinositol 4-phosphate (PI(4)P), which binds to the same site in Osh4p as
Peter Kohut et al.
Biochemical and biophysical research communications, 404(1), 233-238 (2010-11-30)
Uptake of external sterols in the yeast Saccharomyces cerevisiae is a multistep process limited to anaerobiosis or heme deficiency. It includes crossing the cell wall, insertion of sterol molecules into plasma membrane and their internalization and integration into intracellular membranes.
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