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生物源
microbial
品質等級
描述
suitable for testing specifications (CHO C. growth inhibitor)
形狀
solution
濃度
100 mg/mL in DMSO
溶解度
DMSO: soluble
抗生素活性譜
fungi
yeast
作用方式
protein synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
O=C1[C@@]([C@H](O)CC2CC(NC(C2)=O)=O)([H])C[C@@H](C)C[C@@H]1C
InChI
1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChI 密鑰
YPHMISFOHDHNIV-FSZOTQKASA-N
基因資訊
human ... FKBP1A(2280) , PIN1(5300)
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特異性
经测试可用于细胞生长停滞、选择抗环己酰亚胺的酵母、诱导凋亡、以及促进通过FasL凋亡的诱导。
生化／生理作用
环己酰亚胺（CHX）是由灰链霉菌产生的一种抗生素。它的主要生物学活性是真核生物中的翻译抑制，从而导致细胞生长停滞和细胞死亡。CHX被广泛用于抗CHX的酵母和真菌菌株的选择、蛋白质合成的受控抑制以检测短寿命蛋白质和蛋白质表达的超诱导作用、以及诱导凋亡或促进通过死亡受体诱导的凋亡。
其他說明
保存于密闭容器内，置于干燥通风处。打开后的容器必须小心重新密封并保持直立以防止泄漏。储存类别（TRGS 510）：不可燃，急性毒性，1和2类/剧毒有害物质。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
188.6 °F - closed cup
閃點（°C）
87 °C - closed cup
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