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品質等級
化驗
>98% (HPLC)
形狀
solid
顏色
white
溶解度
H2O: soluble 17 mg/mL
DMSO: soluble 20 mg/mL
儲存溫度
2-8°C
SMILES 字串
Cl[H].CCc1cccc(c1)N(C)C(=N)Nc2cccc3ccccc23
InChI
1S/C20H21N3.ClH/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19;/h4-14H,3H2,1-2H3,(H2,21,22);1H
InChI 密鑰
CKAKVKWRMCAYJD-UHFFFAOYSA-N
生化/生理作用
CNS-1102 acts as a neuroprotective agent and might exhibit therapeutic effects against acute stroke and traumatic brain injury.
Noncompetitive NMDA glutamate receptor antagonist.
特點和優勢
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
K W Muir et al.
Annals of the New York Academy of Sciences, 765, 279-289 (1995-09-15)
The high affinity noncompetitive N-methyl-D-aspartate receptor antagonist CNS 1102 (aptiganel hydrochloride, Cambridge NeuroScience, Cambridge, MA.) is neuroprotective in preclinical models of stroke when administered as pretreatment or up to 60 minutes postischemia, and has potential for treatment of acute stroke
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