跳转至内容
Merck
所有图片(5)

主要文件

查看所有文档

C1129

Sigma-Aldrich

胆酸

from bovine and/or ovine, ≥98%

别名:

3α,7α,12α-三羟基-5β-胆烷酸, 胆烷酸

登录查看公司和协议定价
所有图片(5)

About This Item

经验公式（希尔记法）:
C24H40O5
CAS号:
81-25-4
分子量:
408.57
Beilstein:
2822009
EC號碼:
201-337-8
MDL號碼:
MFCD00003672
分類程式碼代碼:
12161900
PubChem物質ID:
24892356
NACRES:
NA.25

生物源

bovine and/or ovine

品質等級

200

描述

anionic

化驗

≥98%

形狀

powder

分子量

408.57 g/mol

mp

200-201 °C (lit.)

官能基

carboxylic acid

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

InChI 密鑰

BHQCQFFYRZLCQQ-OELDTZBJSA-N

基因資訊

human ... CYP1A2(1544)

正在寻找类似产品? 访问 产品对比指南

相关类别

一般說明

胆酸是肝脏中产生的主要的胆汁酸，其可促进脂肪吸收和胆固醇排泄。 它是一种非变性离子型去污剂。

應用

在一项研究中，膳食胆酸已被用于评估其对结肠上皮细胞增殖的影响。 它也被用于研究人类红细胞血影的提取和比较。
用于提取膜蛋白的非变性离子洗涤剂。

生化／生理作用

胆汁酸

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 3

1 of 3

脱氧胆酸 ≥99.0% (T)

Sigma-Aldrich

30960

脱氧胆酸

鹅去氧胆酸 European Pharmacopoeia (EP) Reference Standard

C1050000

鹅去氧胆酸

胆汁酸，结合型

Sigma-Aldrich

CBA

胆汁酸，结合型

R Coleman et al.
Biochimica et biophysica acta, 436(1), 38-44 (1976-06-04)
1. Human erythrocyte ghosts were extracted with individual free and conjugated bile salts and, for comparison, with Triton X-100 under conditions approximating to physiological temperature, pH and tonicity. 2. Treatment with cholate, glycocholate, taurocholate, or with Triton X-100 gave lipid-depleted
Hui Zhou et al.
JCI insight, 5(20) (2020-10-16)
High-fat feeding (HFF) leads to gut dysbiosis through unclear mechanisms. We hypothesize that bile acids secreted in response to high-fat diets (HFDs) may act on intestinal Paneth cells, leading to gut dysbiosis. We found that HFF resulted in widespread taxonomic
E E Deschner et al.
Digestion, 21(6), 290-296 (1981-01-01)
Administration of cholic acid (1.0% of the diet) to male Fisher rats for 3 days resulted in increased numbers of DNA synthesizing epithelial cells per colonic crypt column as compared to those found in either control or 0.2% cholic acid-fed
Michael Lazarou et al.
The FEBS journal, 276(22), 6701-6713 (2009-10-22)
Complex IV is the terminal enzyme of the mitochondrial respiratory chain. In humans, biogenesis of complex IV involves the coordinated assembly of 13 subunits encoded by both mitochondrial and nuclear genomes. The early stages of complex IV assembly involving mitochondrial
Roberto Pellicciari et al.
Journal of medicinal chemistry, 52(24), 7958-7961 (2009-12-18)
In the framework of the design and development of TGR5 agonists, we reported that the introduction of a C(23)(S)-methyl group in the side chain of bile acids such as chenodeoxycholic acid (CDCA) and 6-ethylchenodeoxycholic acid (6-ECDCA, INT-747) affords selectivity for
查看所有相关文献

实验方案

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门