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Merck

B1434

Sigma-Aldrich

BMP7, human

>95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

别名:

BMP-7, OP-1, Osteogenic protein 1

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

product name

Bone Morphogenetic Protein 7 human, >95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

生物源

human

品質等級

重組細胞

expressed in CHO cells

化驗

>95% (SDS-PAGE)

形狀

lyophilized powder

效力

0.2-0.6 μg/mL ED50

分子量

monomer calculated mol wt 15.7 kDa
18-20 kDa by SDS-PAGE (reducing)
30-40 kDa by SDS-PAGE (non-reducing)

包裝

pkg of 10 μg

儲存條件

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

技術

cell culture | mammalian: suitable

雜質

endotoxin, tested

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... BMP7(655)

生化/生理作用

Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

外觀

Lyophilized from 50.0 μl of a 0.2 μm filtered solution in 35% acetonitrile, 0.1% TFA containing 50 μg bovine serum albumin per 1μg of cytokine.

分析報告

The biological activity is measured by its ability to induce alkaline phosphatase production using mouse ATDC-5 chondrogenic cells.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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A J Celeste et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(24), 9843-9847 (1990-12-01)
Characterization of the polypeptides present in bone-inductive protein extracts from bovine bone has led to the cloning of seven regulatory molecules, six of which are distantly related to transforming growth factor beta. The three human bone morphogenetic proteins (BMPs) we
A H Reddi
Nature biotechnology, 16(3), 247-252 (1998-04-07)
Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It has formed the basis for the emerging discipline of tissue engineering, which uses principles of molecular developmental biology and morphogenesis gleaned through
Yan Wang et al.
Experimental and molecular pathology, 98(3), 393-402 (2015-03-17)
This study presented the effect of bone morphogenic protein-7 (BMP-7) inhibiting epithelial-mesenchymal transition (EMT) in silicosis model. In vivo, Wistar rats were exposed to silica by intratracheal instillation. Seven days later rats were treated with BMP-7. Rats were sacrificed at
Endre Kristóf et al.
Scientific reports, 5, 12540-12540 (2015-07-28)
Laser-scanning cytometry is presented as a tool allowing population scale analysis of ex vivo human brown adipogenic differentiation. It combines texture analysis and detection of Ucp1 protein content in single brown adipocytes of mixed cell populations with gene expression pattern
Pilar González-Gómez et al.
Oncotarget, 6(13), 10950-10963 (2015-04-11)
Glioblastoma tumor initiating cells are believed to be the main drivers behind tumor recurrence, and therefore therapies that specifically manage this population are of great medical interest. In a previous work, we synthesized controlled release microspheres optimized for intracranial delivery

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