A9605

AC-93253

≥98% (HPLC)

• 别名: 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazolium iodide
• 经验公式（希尔记法）: C₂₃H₂₅N₂SI
• CAS号: 108527-83-9
• 分子量: 488.43
• MDL號碼: MFCD03769029
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24724406
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• 顏色: dark purple
• 溶解度: DMSO: >10 mg/mL; H₂O: insoluble
• 儲存溫度: 2-8°C
• SMILES 字串: [I-].CC[n+]1c(\C=C\C=C2\N(C)c3ccccc3C2(C)C)sc4ccccc14
• InChI: 1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1
• InChI 密鑰: TWBRXRGFFUATNI-UHFFFAOYSA-M

说明

生化／生理作用

AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC₅₀ = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.

Potent, cell permeable, subtype selective RAR (RARα) agonist.

特點和優勢

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable