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A5285

Sigma-Aldrich

腺苷 5′-二磷酸 单钾盐 二水合物

bacterial, ≥95%, powder

别名:

5′-二磷酸腺苷钾盐, ADP

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About This Item

经验公式（希尔记法）:
C10H14KN5O10P2 · 2H2O
CAS号:
72696-48-1
分子量:
501.32
MDL號碼:
MFCD00066472
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
24890964
NACRES:
NA.77

生物源

bacterial

品質等級

200

化驗

≥95%

形狀

powder

儲存溫度

−20°C

SMILES 字串

[O-]P(OP(OC[C@H]([C@@H](O)[C@H]1O)O[C@H]1N2C3=C(N=C2)C(N)=NC=N3)(O)=O)(O)=O.[K+]

InChI

1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

InChI 密鑰

ZNCWUOPIJTUALR-MCDZGGTQSA-M

基因資訊

human ... HSP90AA1(3320) , P2RY1(5028)

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相关类别

一般說明

二磷酸腺苷（ADP）是活生物体中能量流动的关键一环。其结构包括连接腺嘌呤的糖骨架，以及连接核糖第五个碳原子的两个磷酸基团。ADP可作为ATP生物合成的前体。 ADP可作为特异性靶向P2Y受体的血小板弱激动剂。但是，ADP在血小板功能中起关键作用，由血小板致密颗粒释放时可增强其它血小板激动剂的作用，并促进血小板聚集体的稳定性。

應用

5′-二磷酸腺苷已被用于研究大鼠脑中细胞外β-烟酰胺腺嘌呤二核苷酸(β-NAD+)的释放、神经元效应和去除。 5′-二磷酸腺苷也被用于比较急性冠状动脉综合征后普拉格雷与氯吡格雷抗血小板治疗的效果。
5′-二磷酸腺苷单钾盐二水合物 (ADP)已用于:
  • 滴定以测定渗透性肌纤维中复合物I辅助的呼吸
  • 滴定以测定ADP刺激的呼吸动力学
  • 制备用于测定线粒体呼吸的ADP溶液

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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