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Merck

01897

Sigma-Aldrich

腺苷-5'-二磷酸 二钠盐

≥90%

别名:

ADP二钠盐, 腺苷 5′-ADP, 腺苷 5′-二磷酸二钠盐, 5′-ADP-Na2

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About This Item

经验公式(希尔记法):
C10H13N5Na2O10P2
CAS号:
分子量:
471.16
Beilstein:
7563620
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
NACRES:
NA.51

化驗

≥90%

形狀

powder or crystals

光學活性

[α]20/D −29.6±1°, c = 0.5% in 0.5 M Na2HPO4

雜質

≤10% water

儲存溫度

−20°C

SMILES 字串

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI 密鑰

ORKSTPSQHZNDSC-IDIVVRGQSA-L

相关类别

應用

5′-二磷酸腺苷二钠盐用于在血液样本中的嘌呤能 G 蛋白耦联受体 P2Y12 激动剂血小板活化检测。

生化/生理作用

5′-二磷酸腺苷(ADP)是一种通过 ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP 通过嘌呤受体 P2Y1 与 P2Y12 的相互作用影响血小板活化。 在通过ecto-ADP酶转化为腺苷后,通过腺苷受体抑制血小板活化。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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The underlying mechanism of the myocardial protective effect of fisetin was studied in a rat ischemia/reperfusion injury model. Sprague-Dawley rats were randomly assigned to seven groups and pretreated with different solutions by gavage administration. A rat model of cardiac ischemia/reperfusion
Sarah Jones et al.
British journal of haematology, 153(1), 83-91 (2011-02-22)
ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) paradoxically enhances ADP-evoked aggregation, an effect that has been attributed to

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