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化驗
≥90%
形狀
powder or crystals
光學活性
[α]20/D −29.6±1°, c = 0.5% in 0.5 M Na2HPO4
雜質
≤10% water
儲存溫度
−20°C
SMILES 字串
[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChI 密鑰
ORKSTPSQHZNDSC-IDIVVRGQSA-L
相关类别
應用
5′-二磷酸腺苷二钠盐用于在血液样本中的嘌呤能 G 蛋白耦联受体 P2Y12 激动剂血小板活化检测。
生化/生理作用
5′-二磷酸腺苷(ADP)是一种通过 ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP 通过嘌呤受体 P2Y1 与 P2Y12 的相互作用影响血小板活化。 在通过ecto-ADP酶转化为腺苷后,通过腺苷受体抑制血小板活化。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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British journal of haematology, 153(1), 83-91 (2011-02-22)
ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) paradoxically enhances ADP-evoked aggregation, an effect that has been attributed to
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