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Merck

81709

Sigma-Aldrich

L-脯氨酸

≥99.5% (NT), suitable for cell culture, BioUltra

别名:

( S )-吡咯烷-2-羧酸

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About This Item

经验公式(希尔记法):
C5H9NO2
CAS号:
分子量:
115.13
Beilstein:
80810
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

product name

L-脯氨酸, BioUltra, ≥99.5% (NT)

產品線

BioUltra

品質等級

化驗

≥99.5% (NT)

形狀

powder or crystals

光學活性

[α]20/D −85.0±1.0°, c = 5% in H2O

技術

cell culture | mammalian: suitable

雜質

insoluble matter, passes filter test
≤0.3% foreign amino acids

燃燒殘留物

≤0.1%

損耗

≤0.1% loss on drying, 20 °C (HV)

顏色

colorless to white

pH值

6.0-7.0 (25 °C, 1 M in H2O)

mp

228 °C (dec.) (lit.)

溶解度

H2O: 1 M at 20 °C, clear, colorless

負離子痕跡

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

正離子痕跡

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤20 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

&lambda ;

1 M in H2O

紫外吸收

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

SMILES 字串

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI 密鑰

ONIBWKKTOPOVIA-BYPYZUCNSA-N

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應用


  • Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (M(pro)).: This publication discusses the synthesis of novel compounds using L-Proline and their potential as inhibitors against COVID-19, contributing to the ongoing search for effective treatments (Geedkar et al., 2024).

其他說明

保护酶免收热失活;多种微生物的生长必需

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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CRC Handbook of Microbiology, 4, 1-1 (1974)
L.G. Paleg et al.
Australian Journal of Plant Physiology, 8, 107-107 (1981)
Marie Couturier et al.
The Journal of biological chemistry, 288(20), 14624-14635 (2013-04-06)
The microbial deconstruction of the plant cell wall is a key biological process that is of increasing importance with the development of a sustainable biofuel industry. The glycoside hydrolase families GH5 (PaMan5A) and GH26 (PaMan26A) endo-β-1,4-mannanases from the coprophilic ascomycete
David Saadoun et al.
Annals of the rheumatic diseases, 73(5), 831-837 (2013-04-23)
The standard-of-care treatment of patients with hepatitis C virus (HCV)-mixed cryoglobulinemia (MC) vasculitis includes pegylated interferon α (PegIFN)-α plus ribavirin and/or rituximab. About 30-40% of patients are non-responders or relapsers to such combination. To analyse the safety and efficacy of
Michael P Manns et al.
Gastroenterology, 147(2), 366-376 (2014-04-15)
MK-5172 is an inhibitor of the hepatitis C virus (HCV) nonstructural protein 3/4A protease; MK-5172 is taken once daily and has a higher potency and barrier to resistance than licensed protease inhibitors. We investigated the efficacy and tolerability of MK-5172

商品

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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