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Merck

63535

Sigma-Aldrich

氯化锰 四水合物

BioUltra, for molecular biology, ≥99.0% (KT)

别名:

Manganese chloride tetrahydrate, Manganese dichloride tetrahydrate, MnCl2.4H2O

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About This Item

线性分子式:
MnCl2 · 4H2O
CAS号:
分子量:
197.91
EC號碼:
MDL號碼:
分類程式碼代碼:
12352302
PubChem物質ID:
NACRES:
NA.25

等級

for molecular biology

品質等級

產品線

BioUltra

化驗

≥99.0% (KT)

雜質

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

pH值

4-6 (25 °C, 0.5 M in H2O)

mp

58 °C (lit.)

溶解度

H2O: 0.5 M at 20 °C, clear, colorless

負離子痕跡

sulfate (SO42-): ≤50 mg/kg

&lambda ;

0.5 M in H2O

紫外吸收

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

SMILES 字串

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

InChI 密鑰

CNFDGXZLMLFIJV-UHFFFAOYSA-L

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其他說明

在 DNA 拖尾-推荐用于 dC 和 dG 拖尾的 MnCl 2 缓冲液;在 RNA 逆转录中用耐热 DNA 聚合酶

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

標靶器官

Brain

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

does not flash

閃點(°C)

does not flash

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Terminal transferase: use of the tailing of DNA and for in vitro mutagenesis.
G Deng et al.
Methods in enzymology, 100, 96-116 (1983-01-01)
T W Myers et al.
Biochemistry, 30(31), 7661-7666 (1991-08-06)
A recombinant DNA polymerase derived from the thermophilic eubacterium Thermus thermophilus (Tth pol) was found to possess very efficient reverse transcriptase (RT) activity in the presence of MnCl2. Many of the problems typically associated with the high degree of secondary
Nicholas Sofos et al.
Molecular cell, 79(5), 741-757 (2020-07-31)
Cmr-β is a type III-B CRISPR-Cas complex that, upon target RNA recognition, unleashes a multifaceted immune response against invading genetic elements, including single-stranded DNA (ssDNA) cleavage, cyclic oligoadenylate synthesis, and also a unique UA-specific single-stranded RNA (ssRNA) hydrolysis by the
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related

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