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44707

Sigma-Aldrich

阿维A酸

≥98.0% (HPLC)

别名:

9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基壬酸-2,4,6,8-四烯酸

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About This Item

经验公式（希尔记法）:
C21H26O3
CAS号:
55079-83-9
分子量:
326.43
EC號碼:
259-474-4
MDL號碼:
MFCD00866632
分類程式碼代碼:
41116107
PubChem物質ID:
57650239
NACRES:
NA.25

品質等級

100

化驗

≥98.0% (HPLC)

形狀

powder

SMILES 字串

COc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C

InChI

1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+

InChI 密鑰

IHUNBGSDBOWDMA-AQFIFDHZSA-N

基因資訊

human ... RARA(5914) , RARB(5915) , RARG(5916) , RXRA(6256) , RXRB(6257) , RXRG(6258)

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應用

阿维 A 是一种可与核受体结合并调节基因表达的类视黄醇，是通过 CD95 信号通路的 α-分泌酶 ADAM10 基因表达和凋亡诱导剂的有效激活剂。 阿维 A 是一种用于治疗严重银屑病的全身性维甲酸类药物。

生化／生理作用

合成维甲酸，是依曲甲酸酯的代谢物。 优先与细胞视黄酸结合蛋白（CRABP） 结合。

訊號詞

Danger

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBW6084
BCBS1309V
BCBM5742V
BCBM2107V
BCBL5399V

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视黄醇乙酸酯 synthetic, crystalline solid or supercooled liquid

Sigma-Aldrich

R4632

视黄醇乙酸酯

全反式视黄醛 powder, ≥98%

Sigma-Aldrich

R2500

全反式视黄醛

视黄酸 ≥98% (HPLC), powder

Sigma-Aldrich

R2625

视黄酸

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