260M-1

Glycophorin A (GA-R2) Mouse Monoclonal Antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100; 500
• 共軛: unconjugated
• 抗體表格: culture supernatant
• 抗體產品種類: primary antibodies
• 無性繁殖: GA-R2, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (260M-14); vial of 0.5 mL concentrate (260M-15); bottle of 1.0 mL predilute (260M-17); vial of 1.0 mL concentrate (260M-16); bottle of 7.0 mL predilute (260M-18)
• 製造商／商標名: Cell Marque^™
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• 同型: IgG2bκ
• 控制: bone marrow
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: membranous
• 基因資訊: human ... GYPA(2993)

说明

一般說明

Glycophorins A (GPA) and B (GPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and SU blood groups. Glycophorins span the membrane and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin-like surface and it has been suggested this provides a barrier to cell fusion thus minimizing aggregation between red blood cells in the circulation. Anti-glycophorin A has been used to characterize erythroid cell development and in the diagnosis of erythroid leukemias.

Glycophorins A and B are major sialoglycoproteins expressed across the surface of the human erythrocyte membrane and contain the antigenic determinants that define the MNS blood group system. The high sialic acid content of glycophorin A contributes to the generation of a net negative surface charge across erythrocyte membranes that minimizes interactions between red blood cells and prevents their aggregation. Anti-glycophorin A has utility in identifying cells of the erythroid lineage.

品質

IVD

IVD

IVD

RUO

聯結

Glycophorin A Positive Control Slides, Product No. 260S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany