推荐产品
生物源
mouse
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
9C4, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (255M-14)
vial of 0.5 mL concentrate (255M-15)
bottle of 1.0 mL predilute (255M-17)
vial of 1.0 mL concentrate (255M-16)
bottle of 7.0 mL predilute (255M-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同型
IgG1
控制
papillary carcinoma of thyroid
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic, nuclear
基因資訊
human ... LGALS3(3958)
一般說明
Galectin-3 is a 31 kD beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Anti-Galectin-3 has been demonstrated to be valuable in differentiating between benign and malignant thyroid neoplasms in both histologic sections and fine needle aspiration biopsy material. Anti-Galectin-3 antibody has also been useful in identifying anaplastic large cell lymphoma.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
Galectin-3 Positive Control Slides, Product No. 255S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
F Orlandi et al.
Cancer research, 58(14), 3015-3020 (1998-07-29)
Galectin-3 is a carbohydrate-binding protein endowed with an affinity for beta-galactosides. It has been shown to play an important role in cell-cell and cell-matrix interactions and in pre-mRNA splicing. Furthermore, it is involved in the control of cell growth, neoplastic
Mauro Papotti et al.
European journal of endocrinology, 147(4), 515-521 (2002-10-09)
Cystic thyroid lesions can harbour an occult papillary carcinoma, which fine needle aspiration (FNA) biopsy may fail to detect. Recently, new markers such as galectin-3 lectin have been proposed to distinguish benign from malignant thyroid lesions of follicular origin. The
Marille E Herrmann et al.
Archives of pathology & laboratory medicine, 126(6), 710-713 (2002-05-30)
The expression of galectin-3, a human lectin, has been shown to be highly associated with malignant behavior of thyroid lesions. We studied the immunohistochemical expression pattern of galectin-3 in a variety of follicular-derived thyroid lesions (13 benign and 62 malignant)
A Gasbarri et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 17(11), 3494-3502 (1999-11-05)
Thyroid cancer is the most frequently occurring endocrine malignancy; however, preoperative diagnosis of some lesions, in particular those with follicular histology, is difficult, and a consistent number of not otherwise-specified "follicular nodules" are surgically resected more for diagnosis than therapeutic
A Bartolazzi et al.
Lancet (London, England), 357(9269), 1644-1650 (2001-06-27)
Thyroid cancer is the most common endocrine malignant disease, but preoperative diagnosis remains a challenge. Fine-needle aspiration cytology has greatly improved the clinical management of thyroid nodules, but the preoperative characterisation of follicular lesions is very difficult. Many patients are
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