05511
N-Acetyl-Arg-Gly-Lys(acetyl)-7-amido-4-methylcoumarin trifluoroacetate salt
≥98% (HPLC)
别名:
N2-Acetyl-L-arginylglycyl-N3-acetyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide trifluoroacetate salt, Ac-Arg-Gly-Lys(Ac)-AMC
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所有图片(1)
About This Item
经验公式（希尔记法）:
C28H40N8O7 · xC2HF3O2
CAS号:
分子量:
600.67 (free base basis)
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.32
化驗
≥98% (HPLC)
形狀
powder or crystals
儲存溫度
−20°C
SMILES 字串
OC(=O)C(F)(F)F.CC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1
InChI
1S/C26H38N8O6.C2HF3O2/c1-15-12-23(37)40-21-13-17(8-9-18(15)21)33-25(39)20(7-3-4-10-30-16(2)35)34-22(36)14-32-24(38)19(27)6-5-11-31-26(28)29;3-2(4,5)1(6)7/h8-9,12-13,19-20H,3-7,10-11,14,27H2,1-2H3,(H,30,35)(H,32,38)(H,33,39)(H,34,36)(H4,28,29,31);(H,6,7)/t19-,20-;/m0./s1
InChI 密鑰
OOYFMABGIKUMHP-FKLPMGAJSA-N
應用
Novel fluorogenic assay for histone deacetylase activity.
包裝
Bottomless glass bottle. Contents are inside inserted fused cone.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Dennis Wegener et al.
Chemistry & biology, 10(1), 61-68 (2003-02-08)
Histone deacetylases (HDACs) are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. Recent findings suggest that HDACs could be key targets for chemotherapeutic intervention in malignant diseases. A convenient and sensitive fluorogenic assay for HDAC activity
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