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蒸汽密度
3.5 (vs air)
蒸汽壓力
70 mmHg ( 25 °C)
產品線
ReagentPlus®
化驗
≥99%
形狀
liquid
自燃溫度
~896 °F
expl. lim.
42 %
折射率
n20/D 1.3 (lit.)
pH值
7
bp
77-80 °C (lit.)
mp
−44 °C (lit.)
密度
1.373 g/mL at 25 °C (lit.)
SMILES 字串
OCC(F)(F)F
InChI
1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
InChI 密鑰
RHQDFWAXVIIEBN-UHFFFAOYSA-N
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一般說明
2,2,2-三氟乙醇(TFE)是一种有机化合物,化学式为 CF3CH2OH。TFE 是有机合成中常用的溶剂。它也可以用作蛋白质和多肽实验研究中的助溶剂。
應用
2,2,2-三氟乙醇可作为溶剂:
- 通过醛、丙二腈和间苯二酚或二美酮的无催化剂一锅缩合合成 2-氨基-3-氰基-4H-铬和四氢苯[b]吡喃衍生物。
- 在异相 ZIF-8(沸石咪唑酸框架)催化剂环境下,氨基与甲酸的 N-甲酰化。
- 通过蒽酰胺与烷基、芳基或杂芳基酮或醛的缩合制备 2-取代-2,3-二氢-4(1H)-喹唑啉酮衍生物。
- 用 H2O2(过氧化氢)对含硫化合物进行温和的选择性氧化。
特點和優勢
由于电负性的三氟甲基的存在,2,2,2-三氟乙醇的酸性高于乙醇。
法律資訊
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation
標靶器官
Blood
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
86.0 °F - closed cup
閃點(°C)
30 °C - closed cup
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