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Merck

T63002

Sigma-Aldrich

2,2,2-三氟乙醇

ReagentPlus®, ≥99%

别名:

三氟乙基醇

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About This Item

线性分子式:
CF3CH2OH
CAS号:
分子量:
100.04
Beilstein:
1733203
EC號碼:
MDL號碼:
分類程式碼代碼:
12191601
PubChem物質ID:
NACRES:
NA.21

蒸汽密度

3.5 (vs air)

品質等級

蒸汽壓力

70 mmHg ( 25 °C)

產品線

ReagentPlus®

化驗

≥99%

形狀

liquid

自燃溫度

~896 °F

expl. lim.

42 %

折射率

n20/D 1.3 (lit.)

pH值

7

bp

77-80 °C (lit.)

mp

−44 °C (lit.)

密度

1.373 g/mL at 25 °C (lit.)

SMILES 字串

OCC(F)(F)F

InChI

1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

InChI 密鑰

RHQDFWAXVIIEBN-UHFFFAOYSA-N

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一般說明

2,2,2-三氟乙醇(TFE)是一种有机化合物,化学式为 CF3CH2OH。TFE 是有机合成中常用的溶剂。它也可以用作蛋白质和多肽实验研究中的助溶剂。

應用

2,2,2-三氟乙醇可作为溶剂:
  • 通过醛、丙二腈和间苯二酚或二美酮的无催化剂一锅缩合合成 2-氨基-3-氰基-4H-铬和四氢苯[b]吡喃衍生物。
  • 在异相 ZIF-8(沸石咪唑酸框架)催化剂环境下,氨基与甲酸的 N-甲酰化。
  • 通过蒽酰胺与烷基、芳基或杂芳基酮或醛的缩合制备 2-取代-2,3-二氢-4(1H)-喹唑啉酮衍生物。
  • 用 H2O2(过氧化氢)对含硫化合物进行温和的选择性氧化。

特點和優勢

由于电负性的三氟甲基的存在,2,2,2-三氟乙醇的酸性高于乙醇。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation

標靶器官

Blood

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

86.0 °F - closed cup

閃點(°C)

30 °C - closed cup


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