推荐产品
等級
pharmaceutical primary standard
API 家族
trimethadione
製造商/商標名
EDQM
應用
pharmaceutical (small molecule)
形式
neat
儲存溫度
2-8°C
SMILES 字串
CN1C(=O)OC(C)(C)C1=O
InChI
1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3
InChI 密鑰
IRYJRGCIQBGHIV-UHFFFAOYSA-N
基因資訊
human ... CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911)
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Trimethadione EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包裝
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他說明
Sales restrictions may apply.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
[Fetal trimethadione effects].
Ryoikibetsu shokogun shirizu, (30 Pt 5)(30 Pt 5), 94-95 (2000-11-01)
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 104(2), 205-207 (1993-02-01)
1. Trimethadione (TMO) has the properties required of probe drugs for the evaluation of hepatic oxidizing capacity in vivo. 2. TMO is demethylated to dimethadione (DMO), its only metabolite, in the liver after oral administration. 3. In rats with various
[Fetal trimethadione syndrome].
Ryoikibetsu shokogun shirizu, (33)(33), 704-704 (2001-07-21)
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 115(3), 211-216 (1996-11-01)
Trimethadione (TMO) has the properties required of probe drugs for the evaluation of hepatic drug-oxidizing capacity in humans in vivo. TMO is demethylated to dimethadione (DMO), its only metabolite, in the liver after oral administration. Involvement of two cytochrome P450's--CYP2C9
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