SMB00913

BAA485 (12-Ketodeoxycholic acid)

≥95% (HPLC)

• 别名: BAA485 (12-Ketodeoxycholic acid), (3α,5β)-3-Hydroxy-12-oxocholan-24-oic acid, 12-Dehydrodeoxycholic acid, 12-Oxolithocholic acid, 3α-Hydroxy-12-oxo-5β-cholan-24-oic acid, 3α-Hydroxy-12-oxo-5β-cholanic acid
• 经验公式（希尔记法）: C₂₄H₃₈O₄
• CAS号: 5130-29-0
• 分子量: 390.56
• 分類程式碼代碼: 41141802
• NACRES: NA.25

属性

• 化驗: ≥95% (HPLC)
• 形狀: powder
• 品質: 100
• 成份: (3α,5α)-3-Hydroxy-12-oxocholan-24-oic acid, ≤100%
• 包裝: pkg of 25 mg
• 顏色: white to beige
• mp: 165—167 °C
• 溶解度: methanol: 20 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: C[C@H](CCC(O)=O)C1CC[C@@]([C@]21C)([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2=O
• InChI: 1S/C24H38O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-20,25H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,23+,24-/m1/s1
• InChI 密鑰: CVNYHSDFZXHMMJ-VPUMZWJWSA-N

说明

一般說明

BAA485 (12-oxolithocholic acid) is a microbiome-produced derivative of deoxycholic acid and it is a potent activator of the Pyrin inflammasome. BAA485 induces secretion of IL18 in LPS-primed PBMCs.

Bile acids, natural steroid amphipathic compounds formed through cholesterol oxidation in the liver, play a crucial role in regulating lipid metabolism. They facilitate the digestion, absorption, and transport of lipids, lipid-soluble vitamins, and related molecules in the gastrointestinal tract. These bile acids also impact various aspects of cholesterol, glucose, and energy balance.

應用

BAA485 (12-oxolithocholic acid) finds application in metabolomics, biochemical and microbiome research.

特點和優勢

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

其他說明

For additional information on our range of Biochemicals, please complete this form.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P301 + P312 + P330
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable