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Merck
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主要文件

R0800000

Rifampicin quinone

European Pharmacopoeia (EP) Reference Standard

别名:

Dehydrorifampicin

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About This Item

经验公式(希尔记法):
C43H56N4O12
CAS号:
分子量:
820.92
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

rifampicin

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

InChI

1S/C43H56N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-51H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13+,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1

InChI 密鑰

IHHAOHNZEKYBLG-SBMPKVQQSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Rifampicin quinone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Wei Li et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 42(12), 1292-1297 (2008-03-15)
A qualitative analysis method to identify related substances of rifampicin by correlation of spectra in chromatography was established. Standard chromatographic and spectral data obtained by high-performance liquid chromatography with diode array detection (HPLC-DAD) were developed and used in identification of
E B Tazulakhova et al.
Voprosy virusologii, (6)(6), 672-676 (1980-11-01)
A factor stimulating interferon production (FSIP) has been isolated from cells treated once or twice (at an interval of 6-8 hours) with poly(rI).poly(rC) followed by actinomycin D (2 microgram/ml) or dehydrorifampicin (50 microgram/ml). In a dilution 1:512 the preparation stimulated
[Use of dehydrorifampicin for interferon superinduction].
N A Askarkhodzhaev et al.
Antibiotiki, 25(11), 857-859 (1980-11-01)
P Konrad et al.
Clinical immunology and immunopathology, 46(1), 162-166 (1988-01-01)
Rifampicin as a potential immunosuppressive agent was tested in the rat. A freshly made-up solution of this labile antibiotic in a daily dosage of 20 mg/kg iv did not affect mean graft survival time in a heterotopic heart transplant model.
Leonardo Acuña et al.
Cells, 8(8) (2019-07-28)
: Aggregated forms of the synaptic protein α-synuclein (αS) have been proposed to operate as a molecular trigger for microglial inflammatory processes and neurodegeneration in Parkinson´s disease. Here, we used brain microglial cell cultures activated by fibrillary forms of recombinant

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