PHR2629

羟基脲

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 羟基尿素
• 线性分子式: NH₂CONHOH
• CAS号: 127-07-1
• 分子量: 76.05
• Beilstein: 1741548
• MDL號碼: MFCD00007943
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP BP197; traceable to Ph. Eur. Y0000119; traceable to USP 1332000
• API 家族: hydroxyurea
• 形狀: solid
• CofA: current certificate can be downloaded
• 包裝: pkg of 300 mg
• 應用: pharmaceutical small molecule
• 儲存溫度: 2-8°C
• SMILES 字串: NC(=O)NO
• InChI: 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
• InChI 密鑰: VSNHCAURESNICA-UHFFFAOYSA-N

说明

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

抗肿瘤剂。通过形成自由基硝基氧灭活核糖核苷还原酶，自由基硝基氧可结合到酶活性位点的酪氨酰自由基。这可阻断脱氧核苷酸的合成，从而抑制 DNA 合成，并且诱导细胞周期同步化或 S-期细胞死亡。

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC5960 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H340,H361
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Muta. 1B - Repr. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable