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Key Documents

PHR1291

Supelco

头孢唑啉

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

头孢唑啉

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About This Item

经验公式(希尔记法):
C14H14N8O4S3
CAS号:
分子量:
454.51
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. C0682800
traceable to USP 1097603

API 家族

cefazolin

CofA

current certificate can be downloaded

包裝

pkg of 500 mg

應用

pharmaceutical

格式

neat

儲存溫度

2-8°C

InChI

1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1

InChI 密鑰

MLYYVTUWGNIJIB-BXKDBHETSA-N

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一般說明

Cefazolin is a first-generation cephalosporin β-lactam antibiotic drug that exhibits broad-spectrum antimicrobial activity against Klebsiella pneumoniae. It also acts in vitro against Gram-positive aerobic cocci while shows only a limited action on Gram-negative bacteria.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Cefazolin has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin layer chromatography-densitometry technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB0131 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Simultaneous identification and quantitative analysis of eight cephalosporins in pharmaceutical formulations by TLC-densitometry
Monika D, et al.
JPC-Journal of Planar Chromatography-Modern TLC, 24(1), 23-29 (2011)
Voltammetric behavior and assay of the antibiotic drug cefazolin sodium in bulk form and pharmaceutical formulation at a mercury electrode
El-Desoky HS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 39(5), 1051-1056 (2005)
Streamlining methodology for the multiresidue analysis of β -lactam antibiotics in bovine kidney using liquid chromatography-tandem mass spectrometry
Mastovska K and Lightfield AR
Journal of Chromatography A, 1202(2), 118-123 (2008)

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