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等級
certified reference material
pharmaceutical secondary standard
品質等級
agency
traceable to USP 1111908
蒸汽密度
4.4 (vs air)
蒸汽壓力
0.15 mmHg ( 25 °C)
API 家族
proguanil, chlorhexidine
CofA
current certificate can be downloaded
技術
HPLC: suitable
gas chromatography (GC): suitable
bp
232 °C (lit.)
mp
67-70 °C (lit.)
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-8°C
SMILES 字串
Nc1ccc(Cl)cc1
InChI
1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2
InChI 密鑰
QSNSCYSYFYORTR-UHFFFAOYSA-N
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一般說明
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
應用
p-Chloroaniline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析報告
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他說明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
腳註
To see an example of a Certificate of Analysis for this material enter LRAC3328 in the slot below. This is an example certificate only and may not be the lot that you receive.
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Skin Sens. 1
儲存類別代碼
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
248.0 °F - closed cup
閃點（°C）
120.0 °C - closed cup
Preparation and evaluation of lidocaine hydrochloride in cyclodextrin inclusion complexes for development of stable gel in association with chlorhexidine gluconate for urogenital use
da Silva LFJS, et al.
International journal of nanomedicine, 6(3), 1143-1143 (2011)
HPLC determination of chlorhexidine gluconate and p-chloroaniline in topical ointment
Havlikova L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1169-1173 (2007)
D Mortenson et al.
International endodontic journal, 45(9), 878-882 (2012-04-11)
To determine if the formation of para-chloroaniline (PCA) can be avoided by using an alternative irrigant following sodium hypochlorite but before chlorhexidine. Fifty-five single-rooted teeth were decoronated, instrumented to size 40, .06 taper whilst being irrigated with 14% ethylene-diamine-tetra-acetic acid
Kun Yang et al.
Environmental science & technology, 44(8), 3021-3027 (2010-03-06)
Competitive adsorption between nonpolar organic compounds and polar ionic organic compounds (IOCs) on carbon nanotubes (CNTs) is essential for application of CNTs as superior sorbents and for environmental risk assessment of both CNTs and organic contaminants. It was observed in
Fang Wang et al.
Chemical communications (Cambridge, England), (17)(17), 2040-2042 (2008-06-10)
Chemoselective hydrogenation of para-chloronitrobenzene without any dechlorination over Pt/gamma-ZrP catalyst proceeds effectively, which provides a clean and convenient approach to produce useful para-chloroaniline with excellent activity and selectivity.
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